Welcome to PharmVIP (Pharmacogenomic Variant Analysis and Interpretation Platform)

PharmVIP is designed to be a one-stop platform for pharmacogenomic variant analysis and interpretation in individuals. It consists of three data analysis modules from which user can select one or more modules in the same analysis run. First, the Guideline module is used for allele prediction in genes which have information of CPIC (Clinical Pharmacogenetics Implementation Consortium) drug dosing guidelines. These include gene-drug pairs with strong association between genotypes and drug response phenotypes. PharmVIP will report the predicted allele of each gene with the corresponding CPIC recommendation. The second module is for HLA allele prediction. The alleles of all HLA genes predicted using different methods will be listed with the associated adverse drug reactions reported in the published studies, if available. The third module focuses on the identification of variants (single nucleotide polymorphisms, insertions, deletions) in pharmacogenes and the prediction of their effects to gene function. This integrated pharmacogenomics analysis platform is useful for researchers in identifying variants/alleles in all pharmocogenes and interpreting their consequences in terms of gene function, associated adverse drug reactions, drug response and dosing recommendations.